Which of the following topical anesthetics is known to potentially cause a toxic reaction?

Tetracaine Hydrochloride, commonly referred to by its brand name Cetacaine, is a topical anesthetic that is known for its effectiveness in providing localized pain relief. However, it is also associated with a higher risk of systemic toxicity compared to other topical anesthetics. This is primarily because tetracaine has a longer duration of action and a higher potency. In certain circumstances, if used excessively or incorrectly, it can lead to absorption into the bloodstream, which may result in adverse effects such as cardiovascular depression or central nervous system effects.

Lidocaine, while also widely used as a topical anesthetic, generally has a favorable safety profile when used correctly. Procaine and benzocaine, while effective for surface anesthesia, typically have less potential for toxicity in comparison to tetracaine, especially when used as directed. Thus, tetracaine is particularly notable for its potential to cause a toxic reaction, making it essential for healthcare providers to be aware of dosage limitations and application methods to minimize this risk.